Pharmacodynamics, Biomarkers and Personalised Therapy
|Types||Oxford Qualification - Part-time|
|Dates||Mon 3 to Fri 7 Mar 2014|
|Fees||Stand-alone fee: £1,890.00|
|Application status||Applications being accepted|
|Course contact||If you have any questions about this course, please email firstname.lastname@example.org or telephone +44(0)1865 286955.|
The Pharmacodynamics, Biomarkers and Personalised Therapy course is a one-week module of the MSc in Experimental Therapeutics. Offered by the Department of Oncology and the Department for Continuing Education’s CPD Centre, the week will be led by Dr Elaine Johnstone, Senior Research Fellow at the University of Oxford, and will feature face-to-face lectures and tutorials from some of Oxford's leading clinicians and scientists, as well as a practical visit to one of Oxford's research laboratories.
The module can be taken as a stand-alone short course. It includes group work, discussions, guest lectures, and interaction and feedback with tutors and lecturers.
The pharmacodynamic process of drug therapy provides the link between the pharmacokinetic profile and the therapeutic effect of a drug. It encompasses how the drug produces the required pharmacological effect by identifying how the drug is acting, how we can measure that effect and whether there is a dose response. Furthermore it helps us understand how the pharmacological effect is translated into therapeutic effect and identify modifiers of the therapeutic effects in populations.
This module will provide students with the opportunity to learn more about and discuss the following topics:
- Introduction to how drugs act
- How the pharmacodynamic effect is translated into a therapeutic effect
- Drug actions on receptors and second messengers
- Drug actions on enzymes
- Drug actions on transport processes
- Drug–ligand interactions—different models
- The dose-response curve— different models
- Biomarkers and surrogate endpoints
- Pharmacokinetic-pharmacodynamic modelling
This course can be taken:
This course will be held at the Department for Continuing Education, Rewley House, Oxford. There will also be a practical visit to one of Oxford's research laboratories.
Dr Elaine Johnstone
The course has been designed to:
- introduce the concept of pharmacodynamics and how it can be incorporated into modern clinical trial design to improve selection of drug dose and schedule
- enable students to understand how drugs act and how the pharmacodynamic effect is translated into a therapeutic effect
- enable students to analyse how drug act on receptors, second messengers, enzymes and transport processes
- enable students to understand drug–ligand interactions and models, dose-response curves and biomarkers and surrogate endpoints
- enable students to apply their knowledge to pharmacokinetic-pharmacodynamic modelling
Assessment will be based on submission of a set written assignment, not exceeding 4,000 words.
Those wishing to may apply to take the course with accreditation. The University of Oxford Department for Continuing Education offers Credit Accumulation and Transfer Scheme (CATS) points for the course. Participants attending at least 75% of the taught course and successfully completing assessed assignments are eligible to earn credit equivalent to 20 CATS-equivalent points which may be counted towards a postgraduate qualification.
Those who do not wish to undertake the assessed work required for academic credit will receive a certificate of attendance at the end of the course.
Level and demands
This course is aimed at qualified doctors, especially specialist registrars in clinical pharmacology or in training for other medical sub-specialities; clinical research fellows in other specialities; pharmacists; nurses; graduates working in the pharmaceutical industry.
The course will be taught by a range of scientists leading these areas of research, and there will be significant time programmed to discuss the scientific and sometimes ethical issues raised by this area of medical research. It will include group work, discussions, guest lectures, and interaction and feedback with tutors and lecturers, as well as a practical visit.
A virtual learning environment (VLE) and access to some of the University of Oxford’s online resources will provide support for those taking the course for credit.
Accommodation is available at the Rewley House Residential Centre, within the Department for Continuing Education, in central Oxford. The comfortable, en-suite, study-bedrooms are rated 3-star, and come with free high-speed internet access and TV. Guests can take advantage of the excellent dining facilities and common room bar, where they may relax and network with others on the programme.
The course fee includes tuition, course materials, refreshments and a three course lunch on each day of the course.
Please see the MSc in Experimental Therapeutics page for more information regarding module fees when taking this course as a part of the MSc Programme.
Details of funding opportunities, including grants, bursaries, loans, scholarships and benefit information are available on our financial assistance page.
- Programme Fee
- For students enrolled on the MSc: £1575.00
- For stand-alone students: £1890.00
Apply for this course
To apply for our short courses you should:
- be a graduate or have successfully completed a professional training course
- have experience in a health-related field
- demonstrate a suitable level of English (if this is not your first language).
How to apply
If you would like to apply for the MSc in Experimental Therapeutics please visit the application page.
To apply for this module as a short course please use the documents below.
Places on the course are limited, so early application is strongly recommended. Completed applications must have been received fourteen days before the course starts.
- Your application can only be fully considered when an application form is supplied complete with payment or purchase order number
- Please note no payments are processed until a student has been accepted onto the course
- Your application will require a copy of your CV, and if you wish to take the course for credit, a reference.
Once we have received your completed application it will be considered by the admissions panel.
If your chosen course is full it is possible to submit a completed application form which, if successful, will be added to the waiting list. You will then be given the opportunity to attend should a place become available.
If you would like to discuss your application or any part of the application process before applying please contact:
Sarah Kelly (Administrative Assistant)
Tel: +44 (0)1865 286955 - Email: email@example.com
You can apply for this course in the following ways:
- Apply by post, email or fax
- Application Form .
Short Course Terms & Conditions (important: please read before applying) .